Bill Murray plays Frank Detorri, a fried-chicken-loving father who could be the poster child for heart attacks and clogged arteries. His daughter Shane (Elena Franklin) worries about her Dad's diet because of her mother's early death. No need to worry - the animated inner workings of Frank have him covered.

Title character Osmosis Jones (Chris Rock - voice) who is as cool as a white cell can come is a low-level police officer in "The City of Frank." He has higher aspirations, but also has a strike against him due to his involvement in the premature release of Frank's puke button. Sound like fun? That's only the beginning.

Inside the brain, the control center for The City of Frank, a self-serving Mayor Phlegmming (William Shatner - voice) is more concerned with his own advancement rather than the health of Frank. His sexy assistant Leah (Brandy Norwood - voice) is a much nobler hormone. Jones goes gaga every time she's around.

The ultimate of evil germs, Thrax (Laurence Fishburne - voice) who looks like an animated version of Snoop Doggy Dog, enters Frank's body. Osmosis Jones is convinced this bad guy is ravaging Downtown Frank, but the problem is no one believes him. Meanwhile, on the outside Frank feels a cold coming on. His daughter panics, but he assures her that he is okay, promises to start a new health regimen, and pops a cold pill just in case.

Drix (David Hyde Pierce - voice) a tough red gel cap who wants to make Frank feel better is skeptical of Jones' theory. The two eventually team up and take on the nefarious Thrax. Will Jones and Drix triumph over evil before it's too late for Frank? Visits to the stomach, zits, and hemorrhoids help to provide answers.

Osmosis Jones is a clever film in search of an audience. Is it a movie for kids, adults, or both? The adult humor and the back and forth shots between real life and animation may confuse young children. Although the title of the film is the name of the main character, it doesn't have much meaning out of context. If a viewer can't get a sense of what a film is about through the title, he/she may choose another flick. Even the tag lines aren't revealing enough: "He's one cell of a guy" and "Every body needs a hero." Perhaps more specific marketing would have resulted in better box office receipts.

Who will like Osmosis Jones? Children twelve and up and adults looking for a fun, eXtremely humorous flick will enjoy this film. For those who are squeamish, don't worry. Your popcorn and milk duds are safe since the animation helps to make otherwise graphic bodily functions palatable. If you're a student struggling with anatomy homework, Osmosis Jones will offer an accurate and exciting lesson.

And I promise you'll never look at a pimple the same way again...

Ms. Robbins is a freelance writer living in Boston, where she worked for a time at a local newspaper and at a local radio station.

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